Immunohistochemical and Immunoelectron Microscopic Analysis on the Heterogeneity of Rat Macrophages with Antimacrophage Monoclonal Antibodies, TRPM-1, TRPM-2, and TRPM-3
نویسندگان
چکیده
منابع مشابه
The Ca 2 + - Activated TRP Channels : TRPM 4 and TRPM 5
Cloning, Distribution, and Structure of TRPM4 and TRPM5 .............................204 Ion Permeability, Unitary Properties, and Specific Blockers of TRPM4 and TRPM5 .........................................................................................204 Sensitivity of TRPM4 and TRPM5 to Intracellular Ca 2 + .....................................205 Activation of TRPM4 and TRPM5 by Voltage...
متن کاملTRPM channel function in Caenorhabditis elegans.
The nematode Caenorhabditis elegans contains over 20 genes for TRP (transient receptor potential) channels which include members of all of the subclasses identified in mammalian cells. These proteins include three members of the TRPM (TRP melastatin) family: gon-2 (abnormal gonad development), gtl-1 (gon-2-like 1) and gtl-2. Although studies of these genes are at an early stage, we are beginnin...
متن کاملMg2+ Homeostasis: The Mg2+nificent TRPM Chanzymes
TRPM6 and TRPM7 are distinct from all other ion channels in that they are composed of linked channel and protein kinase domains. Recent studies demonstrate that these 'chanzymes' are essential for Mg(2+) homeostasis, which is critical for human health and cell viability.
متن کاملThe TRPM ion channel subfamily: molecular, biophysical and functional features.
Significant progress in the molecular and functional characterization of a subfamily of genes that encode melastatin-related transient receptor potential (TRPM) cation channels has been made during the past few years. This subgroup of the TRP superfamily of ion channels contains eight mammalian members and has isoforms in most eukaryotic organisms. The individual members of the TRPM subfamily h...
متن کاملDetailed examination of Mg 2 + and pH sensitivity of human TRPM 7 1 channels
24 TRPM7 channel-kinase is a protein highly expressed in cells of hematopoietic lineage, 25 such as lymphocytes. Studies performed in native and heterologous expression 26 systems have shown that TRPM7 forms non-selective cation channels functional in the 27 plasma membrane and activated upon depletion of cellular Mg. In addition to internal 28 Mg, cytosolic pH and the phospholipid PI(4,5)P2 ar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Japan Society of the Reticuloendothelial System
سال: 1987
ISSN: 1883-6801,0386-9725
DOI: 10.3960/jslrt1961.27.295